The impact factors on 5-year survival rate in patients operated with oral cancer
금동호, 노영채, 윤상용, Kim Hyo-Geon, 이정한, 송재민, 이재열, 황대석, 김용덕, 신상훈, Chung In-Kyo, 김욱규,
소속 상세정보
금동호 ( Geum Dong-Ho ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
노영채 ( Roh Young-Chea ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
윤상용 ( Yoon Sang-Yong ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
( Kim Hyo-Geon ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
이정한 ( Lee Jung-Han ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
송재민 ( Song Jae-Min ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
이재열 ( Lee Jae-Yeol ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
황대석 ( Hwang Dae-Seok ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
김용덕 ( Kim Yong-Deok ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
신상훈 ( Shin Sang-Hun ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
( Chung In-Kyo ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
김욱규 ( Kim Uk-Kyu ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
KMID : 0355620130390050207
Abstract
Objectives: The purpose of this study is to analyze clinical impact factors on the survival rate, and to acquire basic clinical data for the diagnosis of oral cancer, for a determination of the treatment plan with long-term survival in oral cancer patients.
Materials and Methods: Through a retrospective review of the medical records, the factors for long-term survival rate were analyzed. Thirty-seven patients, among patient database with oral cancer treated in the Department of Oral and Maxillofacial Surgery at Pusan National University Hospital within a period from March 1998 to March 2008, were selected within the study criteria and were followed-up for more than 5 years. The analyzed factors were gender, age, drinking, smoking, primary tumor site, type of cancer, TNM stage, recurrence of affected region, and metastasis of cervical lymph node. The 5-year survival rate on the impact factors was calculated statistically using the Kaplan-Meier method.
Results: By classification of clinical TNM at the 1st visit, there were 11 (29.7%) cases for stage I, 11 (29.7%) cases for stage II, 3 (8.1%) cases for stage III, and 12 (32.5%) cases for stage IV. The 5-year survival rate of total oral cancer patients after the operation were 75.7%, pathological TNM stage related 5-year survival rate were as follows: stage I 90.0%, stage II 81.8%, stage III 100% and stage IV 45.5%; in which the survival rate difference by each stage was significantly observed. The recurrence of cervical lymph node was the significant impact factor for the survival rate, because only 30.0% the survival rate in recurrent cases existed. During the follow-up, there were 15 (40.5%) patients with confirmed recurrence, and the 5-year survival rate of these patients was decreased as 46.7%.
Conclusion: The classification of clinical and pathological TNM stage, local recurrence after surgery, and metastasis of cervical lymph node after surgery were analyzed as the 3 most significant factors.
키워드
Oral cancer; Survival rate; Neoplasm metastasis; Recurrence; TNM classification
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